Bovine platelet-derived factor showing mitogenic activity on bovine leukemia virus-infected lymphocytes.

Glucocorticoid effects on peripheral blood lymphocytes in cows infected with bovine leukemia virus.

We examined the effects of glucocorticoids on peripheral blood lymphocytes (PBL) in lymphoproliferative conditions associated with bovine leukemia virus (BLV): persistent lymphocytosis (PL) and lymphosarcoma cell leukemia (BLSL). The effects of hydrocortisone 21-sodium succinate (HSS) on spontaneous incorporation (SI) and mitogen-stimulated incorporation of radiolabeled-thymidine and the effect...

Glucocorticoid receptors in peripheral blood lymphocytes from bovine leukemia virus-infected cows with persistent lymphocytosis.

Bovine leukemia virus-infected cows with persistent lymphocytosis have an expanded population of B-lymphocytes in the peripheral blood that is sensitive to glucocorticoids in vitro and in vivo. We examined peripheral blood lymphocytes from cows with persistent lymphocytosis for the presence of specific glucocorticoid receptors. Steroid binding in intact cells was determined by a whole cell comp...

Glucocorticoid Receptors in Peripheral Blood Lymphocytes from Bovine Leukemia Virus-infected Cows with Persistent Lymphocytosis1

Bovine leukemia virus-infected cows with persistent lymphocytosis have an expanded population of B-lymphocytes in the peripheral blood that is sensitive to glucocorticoids in vitro and in vivo. We examined peripheral blood lymphocytes from cows with persistent lymphocytosis for the presence of specific glucocorticoid receptors. Steroid binding in intact cells was determined by a whole cell comp...

Attempt to eradicate bovine leukemia virus-infected cattle from herds.

Determination of Lymphocyte Subsets and Pcna Activity in Sheep Experimentally Infected with Bovine Leukemia Virus (blv)

Lymphocyte phenotypes were determined in sheep experimentally infected with bovine leukemia virus (BLV). BLV infection was detected by serological tests AGID and ELISA. Flow cytometry analysis with the use of specific monoclonal antibodies for CD markers and conjugates labeled with FITC or PE was performed. Proliferating cell nuclear antigen (PCNA) was estimated in lymphocytes of infected and h...